The Greater Naples Chamber  was founded in 1947 and is the largest of 25 chambers in the five-county Southwest Florida region, recognized as among the best of the 300 chambers in Florida.  The Chamber's primary purpose is to foster business advancement and advocate effective government policy to ensure a healthy business climate.

Today, the Chamber is the largest nonprofit advocate for the Collier County business community. With more than 1,200 members representing 50,000 employees, the Chamber is actively involved in local government, regional economic development and providing valuable resources to its members.